Article
Analysis of the genetic ancestry of patients with oral clefts from South American admixed populations.
European journal of oral sciences - 1 Aug 2016
Vieira-Machado Camilla D, de Carvalho Flavia M, Santana da Silva Luiz C, Dos Santos Sidney E, Martins Claudia, Poletta Fernando A, Mereb Juan C, Vieira Alexandre R, Castilla Eduardo E, Orioli Iêda M
Abstract excerpt
Increased susceptibility to cleft lip, with or without cleft palate (CL±P) has been observed in South America, as related to Amerindian ancestry, using epidemiological data, uniparental markers, and blood groups. In this study, it was evaluated whether this increased risk remains when Amerindian ancestry is estimated using autosomal markers and considered in the predictive model. Ancestry was estimated through...
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