Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Carrier Screening is a Deficient Strategy for Determining Sperm Donor Eligibility and Reducing Risk of Disease in Recipient Children.

Genetic testing and molecular biomarkers - 1 Jun 2016

Silver Ari J, Larson Jessica L, Silver Maxwell J, Lim Regine M, Borroto Carlos, Spurrier Brett, Morriss Anne, Silver Lee M

Abstract excerpt

AIMS: DNA-based carrier screening is a standard component of donor eligibility protocols practiced by U.S. sperm banks. Applicants who test positive for carrying a recessive disease mutation are typically disqualified. The aim of our study was to examine the utility of a range of screening panels adopted by the industry and the effectiveness of the screening paradigm in reducing a future child's risk of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cohort Studies
Share to Cystic Fibrosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Carrier Screening

Share to Heterozygote

Share to High-Throughput Nucleotide Sequencing

Share to Mutation

Share to Spermatozoa

Source

Open in PubMed Open full text

Identifiers

PMID: 27104957
DOI: 10.1089/gtmb.2016.0014
PMCID: PMC4892196

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Carrier Screening is a Deficient Strategy for Determining Sperm Donor Eligibility and Reducing Risk of Disease in Recipient Children.PMID 27104957Read ↗

Comprehensive carrier genetic test using next-generation deoxyribonucleic acid sequencing in infertile couples wishing to conceive through assisted reproductive technology.Semantic proximity Read ↗

Application of clinical exome sequencing in sperm donor screening in China.Semantic proximity Read ↗

NGS-Based Assay for the Identification of Individuals Carrying Recessive Genetic Mutations in Reproductive Medicine.Semantic proximity Read ↗

Carrier testing for severe childhood recessive diseases by next-generation sequencing.Semantic proximity Read ↗

Management of the risks for inherited disease in donor-conceived offspring.Semantic proximity Read ↗

Comprehensive Carrier Screening and Molecular Diagnostic Testing for Recessive Childhood DiseasesSemantic proximity Read ↗

The use of expanded carrier screening of gamete donorsSemantic proximity Read ↗

Challenges in providing residual risks in carrier testingSemantic proximity Read ↗

Genetic testing of sperm donors at a human sperm bank in ChinaSemantic proximity Read ↗

Incidental molecular diagnoses and heterozygous risk alleles in a carrier screening cohort.Semantic proximity Read ↗

Targeted mutation screening panels expose systematic population bias in detection of cystic fibrosis risk.Semantic proximity Read ↗

Genetic testing in living kidney donor candidates.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.