Article
A Specific Nutrient Combination Attenuates the Reduced Expression of PSD-95 in the Proximal Dendrites of Hippocampal Cell Body Layers in a Mouse Model of Phenylketonuria.
Nutrients - 26 Mar 2016
Bruinenberg Vibeke M, van Vliet Danique, Attali Amos, de Wilde Martijn C, Kuhn Mirjam, van Spronsen Francjan J, van der Zee Eddy A
Abstract excerpt
The inherited metabolic disease phenylketonuria (PKU) is characterized by increased concentrations of phenylalanine in the blood and brain, and as a consequence neurotransmitter metabolism, white matter, and synapse functioning are affected. A specific nutrient combination (SNC) has been shown to improve synapse formation, morphology and function. This could become an interesting new nutritional approach for PKU....
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