Article
Testing the causality between CYP9M10 and pyrethroid resistance using the TALEN and CRISPR/Cas9 technologies.
Scientific reports - 20 Apr 2016
Itokawa Kentaro, Komagata Osamu, Kasai Shinji, Ogawa Kohei, Tomita Takashi
Abstract excerpt
Recently-emerging genome editing technologies have enabled targeted gene knockout experiments even in non-model insect species. For studies on insecticide resistance, genome editing technologies offer some advantages over the conventional reverse genetic technique, RNA interference, for testing causal relationships between genes of detoxifying enzymes and resistance phenotypes. There were relatively abundant...
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