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Article

Design of antioxidative biointerface for separation of hematopoietic stem cells with high maintenance of undifferentiated phenotype.

Journal of biomedical materials research. Part A - 1 Aug 2016

Ikeda Yutaka, Yoshinari Tomoki, Miyoshi Hirotoshi, Nagasaki Yukio

Abstract excerpt

During cell cultivation, excessively generated reactive oxygen species (ROS) affect cellular properties and functions. Although cell cultivation media contain several types of low-molecular-weight antioxidants, these small antioxidants are internalized into the mitochondria and they disrupt regulated redox balance. Here, we developed a novel biointerface that effectively eliminates ROS on a cell culture surface....

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Identifiers

PMID: 27086723
DOI: 10.1002/jbm.a.35740

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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