Article
Prokineticin receptor 1 is required for mesenchymal-epithelial transition in kidney development.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Aug 2016
Arora Himanshu, Boulberdaa Mounia, Qureshi Rehana, Bitirim Verda, Messadeq Nadia, Dolle Pascal, Nebigil Canan G
Abstract excerpt
Identification of factors regulating renal development is important to understand the pathogenesis of congenital kidney diseases. Little is known about the molecular mechanism of renal development and functions triggered by the angiogenic hormone prokineticin-2 and its receptor, PKR1. Utilizing the Gata5 (G5)-Cre and Wilms tumor 1 (Wt1)(GFP)cre transgenic lines, we generated mutant mice with targeted PKR1 gene...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
