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Article

Genetic Variants of Angiotensin-Converting Enzyme Are Linked to Autism: A Case-Control Study.

PloS one - 1 Jan 2016

Firouzabadi Negar, Ghazanfari Nima, Alavi Shoushtari Ali, Erfani Nasrallah, Fathi Farshid, Bazrafkan Mozhdeh, Bahramali Ehsan

Abstract excerpt

BACKGROUND: Autism is a disease of complex nature with a significant genetic component. The importance of renin-angiotensin system (RAS) elements in cognition and behavior besides the interaction of angiotensin II (Ang II), the main product of angiotensin-converting enzyme (ACE), with neurotransmitters in CNS, especially dopamine, proposes the involvement of RAS in autism. Since the genetic architecture of autism...

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Identifiers

PMID: 27082637
DOI: 10.1371/journal.pone.0153667
PMCID: PMC4833406

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ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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