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Article

Pathogenesis of nonalcoholic steatohepatitis.

Cellular and molecular life sciences : CMLS - 1 May 2016

Liu Wensheng, Baker Robert D, Bhatia Tavleen, Zhu Lixin, Baker Susan S

Abstract excerpt

Nonalcoholic steatohepatitis (NASH) is a severe form of nonalcoholic fatty liver disease and a risk factor for cirrhosis and hepatocellular carcinoma. The pathological features of NASH include steatosis, hepatocyte injury, inflammation, and various degrees of fibrosis. Steatosis reflects disordered lipid metabolism. Insulin resistance and excessive fatty acid influx to the liver are two important contributing...

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Identifiers

PMID: 26894897
DOI: 10.1007/s00018-016-2161-x
PMCID: PMC11108381

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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