Article
Drug resistant strains of Mycobacterium tuberculosis identified through PCR-RFLP from patients of Central Punjab, Pakistan.
International journal of immunopathology and pharmacology - 1 Sept 2016
Riaz Muhammad, Mahmood Zahed, Javed Muhammad Tariq, Javed Irum, Shahid Muhammad, Abbas Mazhar, Ehtisham-Ul-Haque Syed
Abstract excerpt
The study was carried out to determine, by PCR-RFLP, the magnitude of drug resistance in Mycobacterium tuberculosis The study was carried out on 221 random sputum samples collected from patients and 120 suspected cases of drug resistance. Genetic variation in drug-resistant strains was evaluated through PCR-RFLP for isoniazid, ethambutol, streptomycin, and ofloxacin. Out of 341 patients, 91.5% were confirmed as...
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