Article
Decreased proliferative, migrative and neuro-differentiative potential of postnatal rat enteric neural crest-derived cells during culture in vitro.
Experimental cell research - 1 May 2016
Yu Hui, Pan Wei-Kang, Zheng Bai-Jun, Wang Huai-Jie, Chen Xin-Lin, Liu Yong, Gao Ya
Abstract excerpt
A growing body of evidence supports the potential use of enteric neural crest-derived cells (ENCCs) as a cell replacement therapy for Hirschsprung's disease. Based on previous observations of robust propagation of primary ENCCs, as opposed to their progeny, it is suggested that their therapeutic potential after in vitro expansion may be restricted. We therefore examined the growth and differentiation activities...
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