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Article

AKT1 and BRAF mutations in pediatric aggressive fibromatosis.

Cancer medicine - 1 Jun 2016

Meazza Cristina, Belfiore Antonino, Busico Adele, Settanni Giulio, Paielli Nicholas, Cesana Luca, Ferrari Andrea, Chiaravalli Stefano, Massimino Maura, Gronchi Alessandro, Colombo Chiara, Pilotti Silvana, Perrone Federica

Abstract excerpt

Aside from the CTNNB1 and adenomatous polyposis coli (APC) mutations, the genetic profile of pediatric aggressive fibromatosis (AF) has remained poorly characterized. The aim of this study was to shed more light on the mutational spectrum of pediatric AF, comparing it with its adult counterpart, with a view to identifying biomarkers for use as prognostic factors or new potential therapeutic targets. CTNNB1, APC,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27062580
DOI: 10.1002/cam4.669
PMCID: PMC4924379

Genes

CTNNB1
AKT1
BRAF
APC
RET

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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