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Article

Monomerization and ER Relocalization of GRASP Is a Requisite for Unconventional Secretion of CFTR.

Traffic (Copenhagen, Denmark) - 1 Jul 2016

Kim Jiyoon, Noh Shin Hye, Piao He, Kim Dong Hee, Kim Kuglae, Cha Jeong Seok, Chung Woo Young, Cho Hyun-Soo, Kim Joo Young, Lee Min Goo

Abstract excerpt

Induction of endoplasmic reticulum (ER)-to-Golgi blockade or ER stress induces Golgi reassembly stacking protein (GRASP)-mediated, Golgi-independent unconventional cell-surface trafficking of the folding-deficient ΔF508-cystic fibrosis transmembrane conductance regulator (CFTR). However, molecular mechanisms underlying this process remain elusive. Here, we show that phosphorylation-dependent dissociation of GRASP...

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Source

Identifiers

PMID: 27062250
DOI: 10.1111/tra.12403

Genes

CFTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Monomerization and ER Relocalization of GRASP Is a Requisite for Unconventional Secretion of CFTR.PMID 27062250Read ↗

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