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Article

VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research.

Nucleic acids research - 20 Jun 2016

Lai Zhongwu, Markovets Aleksandra, Ahdesmaki Miika, Chapman Brad, Hofmann Oliver, McEwen Robert, Johnson Justin, Dougherty Brian, Barrett J Carl, Dry Jonathan R

Abstract excerpt

Accurate variant calling in next generation sequencing (NGS) is critical to understand cancer genomes better. Here we present VarDict, a novel and versatile variant caller for both DNA- and RNA-sequencing data. VarDict simultaneously calls SNV, MNV, InDels, complex and structural variants, expanding the detected genetic driver landscape of tumors. It performs local realignments on the fly for more accurate allele...

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Identifiers

PMID: 27060149
DOI: 10.1093/nar/gkw227
PMCID: PMC4914105

Genes

BRAF
EGFR
KRAS
MET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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