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Article

GNA14 Somatic Mutation Causes Congenital and Sporadic Vascular Tumors by MAPK Activation.

American journal of human genetics - 4 Aug 2016

Lim Young H, Bacchiocchi Antonella, Qiu Jingyao, Straub Robert, Bruckner Anna, Bercovitch Lionel, Narayan Deepak, McNiff Jennifer, Ko Christine, Robinson-Bostom Leslie, Antaya Richard, Halaban Ruth, Choate Keith A

Abstract excerpt

Vascular tumors are among the most common neoplasms in infants and children; 5%-10% of newborns present with or develop lesions within the first 3 months of life. Most are benign infantile hemangiomas that typically regress by 5 years of age; other vascular tumors include congenital tufted angiomas (TAs), kaposiform hemangioendotheliomas (KHEs), and childhood lobular capillary hemangiomas (LCHs). Some of these...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27476652
DOI: 10.1016/j.ajhg.2016.06.010
PMCID: PMC4974082

Genes

GNA14
GNA11
GNAQ
HRAS
KRAS
NRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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