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Article

Conformational diversity and enantioconvergence in potato epoxide hydrolase 1.

Organic & biomolecular chemistry - 28 Jun 2016

Bauer P, Carlsson Å Janfalk, Amrein B A, Dobritzsch D, Widersten M, Kamerlin S C L

Abstract excerpt

Potato epoxide hydrolase 1 (StEH1) is a biocatalytically important enzyme that exhibits rich enantio- and regioselectivity in the hydrolysis of chiral epoxide substrates. In particular, StEH1 has been demonstrated to enantioconvergently hydrolyze racemic mixes of styrene oxide (SO) to yield (R)-1-phenylethanediol. This work combines computational, crystallographic and biochemical analyses to understand both the...

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Identifiers

PMID: 27049844
DOI: 10.1039/c6ob00060f
PMCID: PMC5315018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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