Article
Genetic evolution of Human Enterovirus A71 subgenotype C4 in Shenzhen, China, 1998-2013.
The Journal of infection - 1 Jun 2016
He Yaqing, Zou Linjie, Chong Marc Ka Chun, Men Ruoting, Xu Wenbo, Yang Hong, Yao Xiangjie, Chen Long, Xian Huixia, Zhang Hailong, Luo Min, Cheng Jinquan, Ma Hanwu, Feng Qianjin, Huang Yun, Wang Yujie, Yeoh Eng-Kiong, Zee Benny Chung-Ying, Zhou Yuanping, He Ming-Liang, Wang Maggie Haitian
Abstract excerpt
BACKGROUND: Human Enterovirus A71 (EV-A71) is one of the severest enteroviruses that causes hand, foot, and mouth disease (HFMD) among children. This study identified the mutations of EV-A71 VP1 amino acid residues over a number of years and explored the possible association of identified mutations and HFMD epidemic outbreaks in Shenzhen, China. METHODS: A total of 3760 stool specimens were collected from HFMD...
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