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Article

Successful transfer to sulfonylureas in KCNJ11 neonatal diabetes is determined by the mutation and duration of diabetes.

Diabetologia - 1 Jun 2016

Babiker Tarig, Vedovato Natascia, Patel Kashyap, Thomas Nicholas, Finn Roisin, Männikkö Roope, Chakera Ali J, Flanagan Sarah E, Shepherd Maggie H, Ellard Sian, Ashcroft Frances M, Hattersley Andrew T

Abstract excerpt

AIMS/HYPOTHESIS: The finding that patients with diabetes due to potassium channel mutations can transfer from insulin to sulfonylureas has revolutionised the management of patients with permanent neonatal diabetes. The extent to which the in vitro characteristics of the mutation can predict a successful transfer is not known. Our aim was to identify factors associated with successful transfer from insulin to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Infant, Newborn, Diseases

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Share to Potassium Channels, Inwardly Rectifying

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Source

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Identifiers

PMID: 27033559
DOI: 10.1007/s00125-016-3921-8
PMCID: PMC4869695

Genes

KCNJ11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Successful transfer to sulfonylureas in KCNJ11 neonatal diabetes is determined by the mutation and duration of diabetes.PMID 27033559Read ↗

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