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Article

Cost-effectiveness of using a gene expression profiling test to aid in identifying the primary tumour in patients with cancer of unknown primary.

The pharmacogenomics journal - 1 Jun 2017

Hannouf M B, Winquist E, Mahmud S M, Brackstone M, Sarma S, Rodrigues G, Rogan P, Hoch J S, Zaric G S

Abstract excerpt

We aimed to investigate the cost-effectiveness of a 2000-gene-expression profiling (GEP) test to help identify the primary tumor site when clinicopathological diagnostic evaluation was inconclusive in patients with cancer of unknown primary (CUP). We built a decision-analytic-model to project the lifetime clinical and economic consequences of different clinical management strategies for CUP. The model was...

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PMID: 27019982
DOI: 10.1038/tpj.2015.94

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