Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Diversity in exon 5 of HLA-C(∗)04:01:01G is significant in anthropological studies.

Human immunology - 1 May 2016

Dunn Paul P J, Lamb Gareth, Selwyn Caroline, Compton Jillian, Yang Edward, Maiers Martin, Fernandez-Vina Marcelo

Abstract excerpt

Polymorphisms in Human Leukocyte Antigen (HLA) class I genes are generally considered to be relevant only if they reside in exons 2 and 3 or if they affect the expression of the allele. HLA-C(∗)04:82 differs from the common HLA-C(∗)04:01:01 by having a 9 nucleotide, or 3 amino acid duplication, in exon 5. Having observed HLA-C(∗)04:82 in a New Zealand Maori stem cell patient, we have attempted to examine the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to New Zealand
Share to Exons
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to Histocompatibility

Share to Histocompatibility Testing

Share to Stem Cell Transplantation

Share to United States

Source

Identifiers

PMID: 27018403
DOI: 10.1016/j.humimm.2016.03.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Diversity in exon 5 of HLA-C(∗)04:01:01G is significant in anthropological studies.PMID 27018403Read ↗

Polymorphic differences within HLA-C alleles contribute to alternatively spliced transcripts lacking exon 5.Semantic proximity Read ↗

Ancient, highly polymorphic human major histocompatibility complex DQA1 intron sequences.Semantic proximity Read ↗

HLA diversity in African Americans.Semantic proximity Read ↗

Sequence-based typing of major histocompatibility complex class I chain-related gene A alleles by use of exons 2-5 information.Semantic proximity Read ↗

Implications of the polymorphism of HLA-G on its function, regulation, evolution and disease associationSemantic proximity Read ↗

Worldwide genetic variation at the 3′ untranslated region of the HLA-G gene: balancing selection influencing genetic diversitySemantic proximity Read ↗

HLA-G 3'-UTR SNP and 14-bp deletion polymorphisms in Portuguese and Guinea-Bissau populations.Semantic proximity Read ↗

High frequency of the HLA-G*01:05N null allele in Beninese populations and its potential impact on reduced soluble HLA-G expression.Semantic proximity Read ↗

Analysis of the frequencies of HLA-A, B, and C alleles and haplotypes in the five major ethnic groups of the United States reveals high levels of diversity in these loci and contrasting distribution patterns in these populations.Semantic proximity Read ↗

A novel allele, HLA-G*010114, with a non-coding DNA base change in exon 2.Semantic proximity Read ↗

Re-examination of HLA-G polymorphism in African Americans.Semantic proximity Read ↗

Ethnic variability in human leukocyte antigen-E haplotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.