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Article

Integrating Evolutionary Game Theory into Mechanistic Genotype-Phenotype Mapping.

Trends in genetics : TIG - 1 May 2016

Zhu Xuli, Jiang Libo, Ye Meixia, Sun Lidan, Gragnoli Claudia, Wu Rongling

Abstract excerpt

Natural selection has shaped the evolution of organisms toward optimizing their structural and functional design. However, how this universal principle can enhance genotype-phenotype mapping of quantitative traits has remained unexplored. Here we show that the integration of this principle and functional mapping through evolutionary game theory gains new insight into the genetic architecture of complex traits. By...

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Identifiers

PMID: 27017185
DOI: 10.1016/j.tig.2016.02.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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