Article
Cross-reactivity and tolerability of aztreonam and cephalosporins in subjects with a T cell-mediated hypersensitivity to penicillins.
The Journal of allergy and clinical immunology - 1 Jul 2016
Romano Antonino, Gaeta Francesco, Valluzzi Rocco Luigi, Maggioletti Michela, Caruso Cristiano, Quaratino Donato
Abstract excerpt
BACKGROUND: The few studies performed in adults with T cell-mediated hypersensitivity to penicillins have found a rate of cross-reactivity with cephalosporins ranging from 2.8% to 31.2% and an absence of cross-reactivity with aztreonam. OBJECTIVE: We sought to evaluate the possibility of using cephalosporins and aztreonam in subjects with documented delayed hypersensitivity to penicillins who especially require...
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