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Pathogenicity and genetic characteristics associated with cell adaptation of a virulent porcine reproductive and respiratory syndrome virus nsp2 DEL strain CA-2.

Veterinary microbiology - 15 Apr 2016

Lee Seung-Chul, Choi Hwan-Won, Nam Eeuri, Noh Yun-Hee, Lee Sunhee, Lee Yoo Jin, Park Gun-Seok, Shin Jae-Ho, Yoon In-Joong, Kang Shien-Young, Lee Changhee

Abstract excerpt

Porcine reproductive and respiratory syndrome virus (PRRSV) is the most common and world-widespread viral pathogen of swine. We previously reported genomic sequences and pathogenicity of type 2 Korean PRRSV strains belonging to the virulent lineage 1 family, which contain remarkable amino acid deletions in nonstructural protein 2 (nsp2 DEL) compared to VR-2332. Here, a virulent type 2 Korean PRRSV nsp2 DEL...

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PMID: 27016772
DOI: 10.1016/j.vetmic.2016.03.002

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PAM
TNF

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