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Article

Anti-Human VEGF Repebody Effectively Suppresses Choroidal Neovascularization and Vascular Leakage.

PloS one - 1 Jan 2016

Hwang Da-Eun, Ryou Jeong-Hyun, Oh Jong Rok, Han Jung Woo, Park Tae Kwann, Kim Hak-Sung

Abstract excerpt

Age-related macular degeneration (AMD) is the leading cause of vision loss and blindness among people over the age of 60. Vascular endothelial growth factor (VEGF) plays a major role in pathological angiogenesis in AMD. Herein, we present the development of an anti- human VEGF repebody, which is a small-sized protein binder consisting of leucine-rich repeat (LRR) modules. The anti-VEGF repebody selected through a...

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Identifiers

PMID: 27015541
DOI: 10.1371/journal.pone.0152522
PMCID: PMC4807815

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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