Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The impact of intrinsic ageing on the protein composition of the dermal-epidermal junction

22 Mar 2016

Abstract excerpt

The dermal-epidermal junction of human skin exhibits age-related remodelling, resulting in a flattened appearance and reduced surface area. Despite this, a paucity of information is available regarding which protein components change with advancing age. Here we report a significant reduction in the protein distribution of collagen IV (P<0.0001), collagen VII (P<0.001), collagen XVII (P<0.01), integrin β4...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Contact Dermatitis and Allergies
Share to Dermatology and Skin Diseases
Share to Skin and Cellular Biology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27013376
DOI: 10.1016/j.mad.2016.03.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The impact of intrinsic ageing on the protein composition of the dermal-epidermal junctionPMID 27013376Read ↗

BP180/type XVII collagen: its role in acquired and inherited disorders or the dermal-epidermal junctionSemantic proximity Read ↗

Collagen diversity in human skin: Aging, wound healing, and disordersSemantic proximity Read ↗

Aging decreases collagen IV expression in vivo in the dermo-epidermal junction and in vitro in dermal fibroblasts: possible involvement of TGF-β1Semantic proximity Read ↗

Role of the extracellular matrix in skin aging and dedicated treatment - State of the artSemantic proximity Read ↗

Integrin α11β1 as a Key Collagen Receptor in Human Skin Dermis: Insight into Fibroblast Function and Skin Dermal AgingSemantic proximity Read ↗

Age-related evolutions of the dermis: Clinical signs, fibroblast and extracellular matrix dynamicsSemantic proximity Read ↗

A review of ageing and an examination of clinical methods in the assessment of ageing skin. Part I: Cellular and molecular perspectives of skin ageingSemantic proximity Read ↗

Collagen XVII.Semantic proximity Read ↗

Global remodelling of cellular microenvironment due to loss of collagen VIISemantic proximity Read ↗

Transcriptome and ultrastructural changes in dystrophic Epidermolysis bullosa resemble skin agingSemantic proximity Read ↗

Collagen XVIII in tissue homeostasis and dysregulation — Lessons learned from model organisms and human patientsSemantic proximity Read ↗

Age-related Changes in the Proteoglycans of Human SkinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.