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Article

Nonencapsulated Streptococcus pneumoniae: Emergence and Pathogenesis

23 Mar 2016

Abstract excerpt

While significant protection from pneumococcal disease has been achieved by the use of polysaccharide and polysaccharide-protein conjugate vaccines, capsule-independent protection has been limited by serotype replacement along with disease caused by nonencapsulatedStreptococcus pneumoniae(NESp). NESp strains compose approximately 3% to 19% of asymptomatic carriage isolates and harbor multiple antibiotic...

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PMID: 27006456
DOI: 10.1128/mbio.01792-15

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