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Breast cancer in a male-to-female transsexual patient with a BRCA2 mutation.

Endocrine-related cancer - 1 May 2016

Corman Vinciane, Potorac Iulia, Manto Florence, Dassy Sarah, Segers Karin, Thiry Albert, Bours Vincent, Daly Adrian F, Beckers Albert

Abstract excerpt

Breast cancer is rare in male patients. Certain predisposing factors, be they genetic (e.g., BRCA2 gene mutations) or hormonal (imbalance between estrogen and androgen levels), have been implicated in male breast cancer pathophysiology. Male-to-female (MtF) transsexualism is a condition that generally involves cross-sex hormone therapy. Anti-androgens and estrogens are used to mimic the female hormonal...

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Source

Identifiers

PMID: 27000661
DOI: 10.1530/ERC-16-0057

Genes

BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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