Article
The Transient Role for Calcium and Vitamin D during the Developmental Hair Follicle Cycle.
The Journal of investigative dermatology - 1 Jul 2016
Mady Leila J, Ajibade Dare V, Hsaio Connie, Teichert Arnaud, Fong Chak, Wang Yongmei, Christakos Sylvia, Bikle Daniel D
Abstract excerpt
The role for 1,25-dihydroxyvitamin D3 and/or calcium in hair follicle cycling is not clear despite their impact on keratinocyte differentiation. We found that calbindin-D9k null (knockout) pups generated from calbindin-D9k knockout females fed a vitamin D-deficient, low-calcium (0.47%) diet develop transient alopecia. The pups appear phenotypically normal until 13 days of age, after which the hair progressively...
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