Molecular and Structural Characterization of a Novel Escherichia coli Interleukin Receptor Mimic Protein

Abstract excerpt

UNLABELLED: Urinary tract infection (UTI) is a disease of extremely high incidence in both community and nosocomial settings. UTIs cause significant morbidity and mortality, with approximately 150 million cases globally per year. Uropathogenic Escherichia coli (UPEC) is the primary cause of UTI and is generally treated empirically. However, the rapidly increasing incidence of UTIs caused by multidrug-resistant...

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