Article
Nodular glomerulosclerosis and renin angiotensin system in Chinese patients with type 2 diabetes.
Molecular and cellular endocrinology - 15 May 2016
Wang Min, Zhang Xiaoxi, Song Xinnan, Zou Xia, Wu Weijie, Wang Yanchao, Lin Bingjie, Li Rong, Hu Fang, Zhao Hailu
Abstract excerpt
BACKGROUND: Diabetic nephropathy (DN) is a multifactorial and polygenic disease with nodular glomerulosclerosis (NGS) pathognomonic for diabetes and hypertension. Patients with type 2 diabetes and hypertension have characteristic renin-angiotensin system (RAS) gene polymorphisms. METHODS AND RESULTS: In this retrospective cohort study, we correlated the presence of NGS with renal function, angiotensin-converting...
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