Article
Hyper-Response to Clopidogrel in Japanese Patients Undergoing Transcatheter Aortic Valve Implantation.
International heart journal - 1 Jan 2016
Watanabe Yusuke, Kozuma Ken, Ishikawa Shuichi, Hosogoe Naoyoshi, Isshiki Takaaki
Abstract excerpt
Dual antiplatelet therapy is empirically recommended following transcatheter aortic valve implantation (TAVI). The aims of the present study were to analyze the effect of clopidogrel on platelet function and to determine the relative contribution of each CYP2C19 loss-of-function genotype undergoing TAVI.Thirty-two patients undergoing TAVI and with clopidogrel treatment were studied. All patients were treated with...
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