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Higher body mass index in older adults is associated with lower gray matter volume: implications for memory performance.

Neurobiology of aging - 1 Apr 2016

Kharabian Masouleh Shahrzad, Arélin Katrin, Horstmann Annette, Lampe Leonie, Kipping Judy A, Luck Tobias, Riedel-Heller Steffi G, Schroeter Matthias L, Stumvoll Michael, Villringer Arno, Witte Anja Veronica

Abstract excerpt

Midlife obesity has been associated with increased dementia risk, yet reports on brain structure and function are mixed. We therefore assessed the effects of body mass index (BMI) on gray matter volume (GMV) and cognition in a well-characterized sample of community-dwelled older adults. GMV was measured using 3T-neuroimaging in 617 participants (258 women, 60-80 years, BMI 17-41 kg/m(2)). In addition, cognitive...

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PMID: 26973099
DOI: 10.1016/j.neurobiolaging.2015.12.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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