Article
A new eosinophilic esophagitis (EoE)-like disease without tissue eosinophilia found in EoE families.
Allergy - 1 Jun 2016
Straumann A, Blanchard C, Radonjic-Hoesli S, Bussmann Ch, Hruz P, Safroneeva E, Simon D, Schoepfer A M, Simon H-U
Abstract excerpt
BACKGROUND: Eosinophilic esophagitis (EoE) is a rapidly emerging, chronic inflammatory, genetically impacted disease of the esophagus, defined clinically by symptoms of esophageal dysfunction and, pathologically, by an eosinophil-predominant tissue infiltration. However, in four EoE families, we have identified patients presenting with EoE-typical and corticosteroid-responsive symptoms, but without tissue...
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