Article
The promise of omics-based approaches to cancer prevention.
Seminars in oncology - 1 Feb 2016
Meerzaman Daoud, Dunn Barbara K, Lee Maxwell, Chen Qingrong, Yan Chunhua, Ross Sharon
Abstract excerpt
Cancer is a complex category of diseases caused in large part by genetic or genomic, transcriptomic, and epigenetic or epigenomic alterations in affected cells and the surrounding microenvironment. Carcinogenesis reflects the clonal expansion of cells that progressively acquire these genetic and epigenetic alterations-changes that, in turn, lead to modifications at the RNA level. Gradually advancing technology...
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