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Article

Personalized therapies in the cancer "omics" era

1 Jan 2010

Abstract excerpt

A molecular hallmark of cancer is the presence of genetic alterations in the tumoral DNA. Understanding how these alterations translate into the malignant phenotype is critical for the adequate treatment of oncologic diseases. Several cancer genome sequencing reports have uncovered the number and identity of proteins and pathways frequently altered in cancer. In this article we discuss how integration of these...

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PMID: 20670437
DOI: 10.1186/1476-4598-9-202

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