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Genetic variability in E6, E7, and L1 genes of human papillomavirus genotype 52 from Southwest China.

Gene - 1 Jul 2016

Zhang Yiwen, Cao Man, Wang Mengting, Ding Xianping, Jing Yaling, Chen Zuyi, Ma Tengjiao, Chen Honghan

Abstract excerpt

Human papillomavirus (HPV) is the major causative agent of cervical cancer, which accounts for the second highest cancer burden in women worldwide. HPV-52, the prevalent subtype in Asia, especially in southwest China, was analyzed in this study. To analyze polymorphisms, intratypic variants, and genetic variability in the E6-E7 (n=26) and L1 (n=53) genes of HPV-52, these genes were sequenced and the sequences...

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PMID: 26968892
DOI: 10.1016/j.gene.2016.03.007

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