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Article

Genetic variability of human papillomavirus type 18 based on E6, E7 and L1 genes in central China.

Virology journal - 5 Jul 2024

Li Ting, Yang Zhiping, Luo Ping, Yang Yang, Lin Zicong, Mei Bing

Abstract excerpt

BACKGROUND: High-risk human papillomavirus (HR-HPV) infection is an important factor for the development of cervical cancer. HPV18 is the second most common HR-HPV after HPV16. METHODS: In this study, MEGA11 software was used to analyze the variation and phylogenetic tree of HPV18 E6-E7 and L1 genes. The selective pressure to E6, E7 and L1 genes was estimated using pamlX. In addition, the B cell epitopes of L1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38970084
DOI: 10.1186/s12985-024-02424-9
PMCID: PMC11227198

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