Article
Emergence of a small colony variant of vancomycin-intermediate Staphylococcus aureus in a patient with septic arthritis during long-term treatment with daptomycin.
The Journal of antimicrobial chemotherapy - 1 Jul 2016
Lin Yu-Tzu, Tsai Jui-Chang, Yamamoto Tatsuo, Chen Hsiao-Jan, Hung Wei-Chun, Hsueh Po-Ren, Teng Lee-Jene
Abstract excerpt
OBJECTIVES: Small colony variants (SCVs) of Staphylococcus aureus are associated with persistent and drug-resistant infections. We demonstrated for the first time the emergence of SCVs in a patient with vancomycin-intermediate S. aureus (VISA) infection during long-term treatment with daptomycin. METHODS: A 73-year-old man with septic arthritis was infected with VISA. The patient was treated with daptomycin;...
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