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Article

Zebrafish Tg(hb9:MTS-Kaede): a new in vivo tool for studying the axonal movement of mitochondria.

Biochimica et biophysica acta - 1 Jun 2016

Bergamin Giorgia, Cieri Domenico, Vazza Giovanni, Argenton Francesco, Mostacciuolo Maria Luisa

Abstract excerpt

OBJECTIVES: Deregulation of axonal transport in neurons is emerging as the major cause of many neurodegenerative diseases in human, such as Charcot-Marie-Tooth (CMT) neuropathy. However, little is known about how mitochondria move in vivo and whether cell culture systems truly represent what happens in living animals. Here we describe the generation of a new zebrafish transgenic line that specifically allows to...

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Identifiers

PMID: 26968460
DOI: 10.1016/j.bbagen.2016.03.007

Genes

MFN2

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