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Article

Mutations in histone modulators are associated with prolonged survival during azacitidine therapy.

Oncotarget - 19 Apr 2016

Tobiasson Magnus, McLornan Donal P, Karimi Mohsen, Dimitriou Marios, Jansson Monika, Ben Azenkoud Asmaa, Jädersten Martin, Lindberg Greger, Abdulkadir Hani, Kulasekararaj Austin, Ungerstedt Johanna, Lennartsson Andreas, Ekwall Karl, Mufti Ghulam J, Hellström-Lindberg Eva

Abstract excerpt

Early therapeutic decision-making is crucial in patients with higher-risk MDS. We evaluated the impact of clinical parameters and mutational profiles in 134 consecutive patients treated with azacitidine using a combined cohort from Karolinska University Hospital (n=89) and from King's College Hospital, London (n=45). While neither clinical parameters nor mutations had a significant impact on response rate, both...

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Share to Antimetabolites, Antineoplastic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26959885
DOI: 10.18632/oncotarget.7899
PMCID: PMC5008347

Genes

ASXL1
RUNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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