Article
High Amounts of Total and Extracellular Vesicle-Derived Soluble HLA-G are Associated with HLA-G 14-bp Deletion Variant in Women with Embryo Implantation Failure.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Jun 2016
Nardi Fabiola da Silva, Slowik Renata, Michelon Tatiana, Manvailer Luis Felipe Dos Santos, Wagner Bettina, Neumann Jorge, Horn Peter, Bicalho Maria da Graça, Rebmann Vera
Abstract excerpt
PROBLEM: Human leukocyte antigen-G (HLA-G) expression is related to 14-bp insertion/deletion polymorphism at the 3'UTR of the HLA-G gene. Soluble forms of HLA-G are released as free molecules or via extracellular vesicles (EVs). Due to the crucial role of HLA-G during pregnancy, we analyzed the 14-bp polymorphism and the two secreted forms in implantation failure women (IF) and in fertile women (FW). METHOD OF...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.