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Article

An Association Study of the SLC19A1 Gene Polymorphisms/Haplotypes with Idiopathic Recurrent Pregnancy Loss in an Iranian Population.

Genetic testing and molecular biomarkers - 1 May 2016

Mohtaram Shirin, Sheikhha Mohammad Hasan, Honarvar Negar, Sazegari Ali, Maraghechi Neda, Feizollahi Zahra, Ghasemi Nasrin

Abstract excerpt

AIMS: The genetics of folate metabolism is one of the most significant mechanisms influencing fetal growth and may underlie some cases of unexplained recurrent miscarriage. Reduced folate carrier 1, encoded by the SLC19A1 gene, is a transporter of folate. Folate deficiency and elevated levels of homocysteine could be disadvantageous for the female reproductive system health. Thus, the balance between homocysteine...

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PMID: 26959650
DOI: 10.1089/gtmb.2015.0230

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