Article
The significance of 1793G>A polymorphism in MTHFR gene in women with first trimester recurrent miscarriages.
Neuro endocrinology letters - 1 Jan 2010
Seremak-Mrozikiewicz Agnieszka, Drews Krzysztof, Kurzawinska Grazyna, Bogacz Anna, Grzeskowiak Edmund, Mrozikiewicz Przemyslaw M
Abstract excerpt
BACKGROUND: Recurrent miscarriages (RM) are significant social and clinical problem. One of suggested reason of RM is hyperhomocysteinemia. Polymorphic genes involved in homocysteine and folate metabolism, including 5,10-methylenetetrahydrofolate reductase (MTHFR) gene, are considered as an important risk factors for homocysteine accumulation and modulator of RM susceptibility. Therefore the aim of this study was...
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