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Article

Constitutive expression of Wnt/β-catenin target genes promotes proliferation and invasion of liver cancer stem cells

7 Mar 2016

Abstract excerpt

Wnt/β‑catenin is an important signaling pathways involved in the tumorgenesis, progression and maintenance of cancer stem cells (CSCs). In the present study, the role of Wnt/β‑catenin signaling in CSC‑mediated tumorigenesis and invasion in liver CSCs was investigated. A small population of cancer stem‑like side population (SP) cells (3.6%) from liver cancer samples were identified. The cells were highly resistant...

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PMID: 26956539
DOI: 10.3892/mmr.2016.4986

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