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Article

Trophoblastic-like transdifferentiation: A key to oncogenesis.

Critical reviews in oncology/hematology - 1 May 2016

Piechowski Jean

Abstract excerpt

The epigenetic plasticity of cancer stem-like cells allows them to reprogram multifaceted properties. Being determined by an oncogene driving force, the reprogrammed properties are suitable for extensive, non-homeostatic clone expansion rather than controlled tissue generation. They belong to physiological phenotypes, under strict control in normal cells but illicitly expressed in malignant cells. Comparing the...

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PMID: 26948538
DOI: 10.1016/j.critrevonc.2016.01.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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