Article
Role of CTCF in Regulating SLC45A3-ELK4 Chimeric RNA.
PloS one - 1 Jan 2016
Qin Fujun, Song Yansu, Zhang Yanmei, Facemire Loryn, Frierson Henry, Li Hui
Abstract excerpt
The chimeric RNA, SLC45A3-ELK4, was found to be a product of cis-splicing between the two adjacent genes (cis-SAGe). Despite the biological and clinical significance of SLC45A3-ELK4, its generating mechanism has not been elucidated. It was shown in one cell line that the binding of transcription factor CTCF to the insulators located at or near the gene boundaries, inversely correlates with the level of the...
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