Article
Association between p53-binding protein 1 expression and genomic instability in oncocytic follicular adenoma of the thyroid.
Endocrine journal - 31 May 2016
Mussazhanova Zhanna, Akazawa Yuko, Matsuda Katsuya, Shichijo Kazuko, Miura Shiro, Otsubo Ryota, Oikawa Masahiro, Yoshiura Koh-Ichiro, Mitsutake Norisato, Rogounovitch Tatiana, Saenko Vladimir, Kozykenova Zhanna, Zhetpisbaev Bekbolat, Shabdarbaeva Dariya, Sayakenov Nurlan, Amantayev Bakanay, Kondo Hisayoshi, Ito Masahiro, Nakashima Masahiro
Abstract excerpt
Oncocytic follicular adenomas (FAs) of the thyroid are neoplasms of follicular cell origin that are predominantly composed of large polygonal cells with eosinophilic and granular cytoplasm. However, the pathological characteristics of these tumors are largely unexplored. Both the initiation and progression of cancer can be caused by an accumulation of genetic mutations that can induce genomic instability. Thus,...
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