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Article

Significance of p53-binding protein 1 (53BP1) expression in thyroid papillary microcarcinoma: association with BRAFV600E mutation status.

Histopathology - 1 Nov 2013

Mussazhanova Zhanna, Matsuda Katsuya, Naruke Yuki, Mitsutake Norisato, Stanojevic Boban, Rougounovitch Tatiana, Saenko Vladimir, Suzuki Keiji, Nishihara Eijyun, Hirokawa Mitsuyoshi, Ito Masahiro, Nakashima Masahiro

Abstract excerpt

AIMS: In a previous report, we proposed that analysis of 53BP1 expression by immunofluorescence could be a useful tool in estimating the level of genomic instability (GIN), as well as the malignant potential, of thyroid tumours. In an attempt to clarify the value of 53BP1 expression as a new molecular marker for the aggressiveness of thyroid papillary microcarcinoma (PMC), we assessed the association between the...

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Share to Carcinoma, Papillary
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intracellular Signaling Peptides and Proteins

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Share to Proto-Oncogene Proteins B-raf

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Source

Identifiers

PMID: 24004175
DOI: 10.1111/his.12233

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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