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Article

Insulin resistance and sarcopenia: mechanistic links between common co-morbidities

1 Mar 2016

Abstract excerpt

Insulin resistance (IR) in skeletal muscle is a key defect mediating the link between obesity and type 2 diabetes, a disease that typically affects people in later life. Sarcopenia (age-related loss of muscle mass and quality) is a risk factor for a number of frailty-related conditions that occur in the elderly. In addition, a syndrome of 'sarcopenic obesity' (SO) is now increasingly recognised, which is common...

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PMID: 26931135
DOI: 10.1530/joe-15-0533

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