Diagnosis of Bacterial Bloodstream Infections: A 16S Metagenomics Approach

Abstract excerpt

BACKGROUND: Bacterial bloodstream infection (bBSI) is one of the leading causes of death in critically ill patients and accurate diagnosis is therefore crucial. We here report a 16S metagenomics approach for diagnosing and understanding bBSI. METHODOLOGY/PRINCIPAL FINDINGS: The proof-of-concept was delivered in 75 children (median age 15 months) with severe febrile illness in Burkina Faso. Standard blood culture...

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