Article
Renalase attenuates hypertension, renal injury and cardiac remodelling in rats with subtotal nephrectomy.
Journal of cellular and molecular medicine - 1 Jun 2016
Yin Jianyong, Lu Zeyuan, Wang Feng, Jiang Zhenzhen, Lu Limin, Miao Naijun, Wang Niansong
Abstract excerpt
Chronic kidney disease is associated with higher risk of cardiovascular complication and this interaction can lead to accelerated dysfunction in both organs. Renalase, a kidney-derived cytokine, not only protects against various renal diseases but also exerts cardio-protective effects. Here, we investigated the role of renalase in the progression of cardiorenal syndrome (CRS) after subtotal nephrectomy....
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